Background: People experiencing or perceived to have a mental illness often subject to stigma from many sources which can be automatically internalized and result in internalized stigma. Aim: This study aimedat assessing the levels of internalized stigma and explores relation between demographic, clinical data, and internalized stigma among psychiatric inpatients in Minia governorate. Research Design: A descriptive correlational research design was used in this study. Study subjects and setting: 50 psychiatric inpatients at Minia Hospital for Mental Health and Addiction Treatment in New Minia City were included in the study. Tools: Socio-demographic and clinical data questionnaire and Internalized Stigma of Mental Illness Scale were used. Results: More than half (60%) of the studied patients were males, near to one third (30%) had schizophrenia, less than two thirds (60%) of them had a moderate level of internalized stigma, while 26% of them had high level of internalized stigma and only 14% of them had low level of internalized stigma. Conclusion: There were no statistically significant differences between internalized stigma levels and all sociodemographic and clinical data of the patients except for occupation and duration of hospitalization. Recommendations: Designing and implementing psycho-educational programs for psychiatric mentally ill patients to decrease internalized stigma are needed.