Background: Cataract is a common serious eye disease among older adults and considered the major cause of blindness globally. The rate and risk of cataract surgery complications is greater among elderly people. Aim of the study: to evaluate the effect of post cataract surgery discharge instructions on reducing eye infection among elderly patients. Research design: Quasi-experimental research design was utilized in the current study. Subjects: A purposive sample of one hundred elderly patients was involved in the current study. Setting: The current study was carried out at ophthalmology department at Minia University Hospital.  Tools of data collection: Three tools were utilized to collect data, First Tool: A Structured interviewing questionnaire sheet, included two main parts: socio-demographic data and medical profile, Second Tool: self-care compliance scale, Third Tool:Post-operative assessment tool. Results: There were highly statistically significant differences between study and control groups regarding post cataract infection manifestations at the three observations post operatively. Conclusion: The study findings concluded that, application of post cataract discharge instructions reflected significant impact on patient's outcomes, in which study group had low incidence rate of eye infection compared to control group. Recommendations: A continuous education and training should be offered on a regular basis for elderly patients undergoing cataract surgery.