Background: Many factors influence the practice of nursing and the education of nursing students. The aim of this study is: to assess the factors affecting quality of education program for nursing students at Minia University. Design: A descriptive design was utilized for the purpose of current study. Setting: this study was carried out on the faculty of nursing Minia University. The Sample of student that participated in the study represented four academic levels (300students out of 964students) as follows: second level 91 out of 292, third level79 out of 270, fourth level70 out of 226 and internship student 60 out of 176. Tool of the study Data was collected through the utilization one tool that divided into two parts: part one: personal data and part two: Student self-assessment tool to assess the factors affecting quality of nursing education. Results: 2^nd year students had high percentage regarding evaluation system, 3^rd year student had high percentage regarding clinical infrastructure, while 4^th year student had high percentage regarding incidental teaching and guidance and counseling and internship students had high percentage regarding change in curriculum and incidental teaching were present and very essential with statistical significance differences Conclusion: 2^nd year students' determined 1^st factor affecting quality of educational program was evaluation system, 2^nd factor was qualified & experienced teachers, 3^rd factor was physical facilities and 4^th factor was change in curriculum. While, 3^rd year students' determined 1^st factor affecting quality of educational program was incidental teaching, 2^nd factor was qualified & experienced teachers, 3^rd factor was physical facilities and 4^th factor was teaching methods. Recommendations: Apply different teaching methods and styles as peer teaching and develop national standard regarding requirement in nursing students as student aptitude, personality, intelligence, and ability to follow instructions