Human-induced land use/ land cover changes resulted in various impacts on the environment at various spatial and temporal scales. Conversion of natural resources for food, urbanization and other socioeconomic benefits have all exacerbated the problem. This paper aims to detect the relationship between NDVI and LST in Al Jabal Al Akhdar Region using remote sensing and GIS tools. The spatiotemporal dynamics of vegetation (NDVI) and LST were studied and understood using a geographic information system (GIS) techniques and remote sensing data in this work. The results showed that the area of dense vegetation decreased from 1207.9 km2 in 2010 to 673.9 km2 in 2020. In 2010, 52.9% of the total area had LST less than 40°C while 47.1% of the total area had LST more than 40°C. In 2020, 8.2% of the total area had LST less than 40°C while 91.8% of the total area had LST more than 40°C. The outcome of this research provides us with new knowledge that helps us better understand the spatiotemporal land use land cover changes and their impacts on LST.