This work evaluates the efficacy of aqueous and ethanolic extracts of fourteen medicinal plants as antifungal agents against Fusarium oxysporum f. sp. lycopersici. Extracts were used at five concentrations (0.0, 0.5, 1.5, 2.5, 5% w/v). Allium sativum was the most efficient when used in both aqueous and ethanolic extracts, followed by Datura stramonium whereas the least effective species were Lantana camara and Ficus elastica. In general, the ethanolic extract exhibited a more potent inhibitory effect on the growth of F. oxysporum f. sp. lycopersici than the aqueous extract, and this was particulary evident for Citrus reticulata, Eucalyptus rostrata, Mentha piperita, Cupressus macrocarpa and Eugenia jambolana. However, Allium sativum and Datura stramonium were the most potent species in addition to Malva parviflora, Althaea rosea, Nigella sativa and Artemisia herba-alba. The dose-response relationship differed according to plant species and the extract used.