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277793

Prevalence of SEN Virus and Torque Teno Virus in Hemodialysis Patients and Healthy Blood Donors in Menoufia University Hospitals

Article

Last updated: 28 Dec 2024

Subjects

-

Tags

Clinical microbiology

Abstract

Background: Blood transfusion and hemodialysis are considered major sources for blood-borne infections by different ways as the equipment, surfaces, and personnel, not only for HCV and HBV but also for SENV and TTV. Objectives: To determine the prevalence of SENV-D/H and TTV among HD patients and blood Donors (control group) in relation to HBV and HCV infection in Menoufia University Hospitals. Methodology: Serum samples from all tested HD patients and blood donors were investigated for ALT, AST by automated chemistry analyzer, anti HBsAg. and HCV antibodies by immunoassay. Also, SENV-D/H and TTV were detected by nested PCR. Results: Total SENV prevalence was 67.5% & 9.6% for HD patients and controls respectively. TTV had a prevalence of 38.9% in HD group and 17.8% in controls. SENV& TTV coinfection was 12.1% and 3.8% for HD patients and controls respectively. Non-significant association between different SENV genotypes, TTV infections and HBV or HCV infections. The positivity of SENV and TTV infections were significantly related to increased duration of hemodialysis, history of blood transfusion and elevated AST and ALT. Conclusions: SENV and TTV are more prevalent in hemodialysis patients than controls. Duration of hemodialysis, history of blood transfusion, and elevated ALT and AST are significantly related to SENV and TTV infection. They have non-significant role in increasing the severity of HBV or HCV infection among hemodialysis patients.

DOI

10.21608/ejmm.2023.277793

Keywords

prevalence, SENV-D, SENV-H, TTV & hemodialysis

Authors

First Name

Shymaa

Last Name

Elaskary

MiddleName

Abd Elsattar

Affiliation

medical microbiology and immunology faculty of medicine Menoufia University

Email

dr.shaimaaelaskary@yahoo.com

City

-

Orcid

0000-0003-0588-9761

First Name

Doaa

Last Name

Elgendy

MiddleName

Salah

Affiliation

Internal Medicine Department, Faculty of Medicine, Menoufia University.

Email

doaa.algendy@med.menofia.edu.eg

City

Shibin El kom

Orcid

0000-0003-0954-6838

First Name

Fathia

Last Name

Elbassal

MiddleName

Ibrahim

Affiliation

Clinical Pathology Department, Faculty of Medicine, Menoufia University

Email

drfathiabassal@yahoo.com

City

Shibin El kom

Orcid

-

First Name

Reda

Last Name

Ibrahem

MiddleName

Abdel Latif

Affiliation

Public Health and Community Medicine Department, Faculty of Medicine, Menoufia University

Email

reda_8083@yahoo.com

City

Shibin El kom

Orcid

0000-0003-1224-7695

Volume

32

Article Issue

1

Related Issue

38243

Issue Date

2023-01-01

Receive Date

2023-01-01

Publish Date

2023-01-01

Page Start

141

Page End

150

Print ISSN

1110-2179

Online ISSN

2537-0979

Link

https://ejmm.journals.ekb.eg/article_277793.html

Detail API

https://ejmm.journals.ekb.eg/service?article_code=277793

Order

277,793

Type

New and original researches in the field of Microbiology.

Type Code

2,038

Publication Type

Journal

Publication Title

Egyptian Journal of Medical Microbiology

Publication Link

https://ejmm.journals.ekb.eg/

MainTitle

Prevalence of SEN Virus and Torque Teno Virus in Hemodialysis Patients and Healthy Blood Donors in Menoufia University Hospitals

Details

Type

Article

Created At

23 Jan 2023