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247177

Bacterial Profile and Antibiotics Susceptibility Pattern of Pleural Effusion Isolates from Sohag University Hospital

Article

Last updated: 28 Dec 2024

OverviewSimilar Items

Subjects

-

Tags

Clinical microbiology

Abstract

Background: Diagnosis of pleural effusion (PE) infection and the isolated organisms reported a significant resistance to the commonly used antibiotics, and the choice of appropriate antibiotics for the management should be guided by microbiological results. Objectives: This study aimed to detect the bacterial profile and antibiotics susceptibility pattern of PE isolates and the prevalence of methicillin-resistant Staph. aureus. Methodology: Plural fluid samples from 121 patients with PE infection were collected for microbiological identification and antibiotic sensitivity testing by Vitek 2 system, Staphylococcal aureus isolates were tested for MecA gene by RT-PCR.  Results: 47% of PE samples exhibited positive culture, the most encountered organisms were Staph. aureus (24.2%), Klebsiella pneumoniae (16.1%), Staph aureus had the highest sensitivity to Vancomycin and Linezolid (100%) and (40%) of Staph aureus had mecA gene. Conclusion: Bacteria isolated from PE exhibited increasing levels of antibiotic resistance that should be reflected in the choice of empirical antimicrobial treatment.

DOI

10.21608/ejmm.2022.247177

Keywords

Bacterial isolates, Antibiotic resistance, Pleural Fluid

Authors

First Name

Ashraf

Last Name

Khodeary

MiddleName

-

Affiliation

Clinical Pathology Department, Faculty of Medicine, Sohag University, Egypt

Email

khodery11@gmail.com

City

-

Orcid

-

First Name

Tamer

Last Name

Mohamed

MiddleName

-

Affiliation

Medical Microbiology and Immunology department, Faculty of Medicine, Sohag University, Sohag , Egypt

Email

tamermmm2000@yahoo.com

City

-

Orcid

0000-0002-2668-1292

First Name

Khaled

Last Name

Alkhayat

MiddleName

-

Affiliation

Chest Department, Faculty of Medicine, Sohag University, Egypt

Email

kfalkhayat@yahoo.com

City

-

Orcid

-

First Name

Sherif

Last Name

Sayed

MiddleName

-

Affiliation

Lecturer, Clinical Pathology Department, Faculty of Medicine, Sohag University, Egypt

Email

shereefaziz_2@yahoo.com

City

-

Orcid

-

Volume

31

Article Issue

3

Related Issue

35368

Issue Date

2022-07-01

Receive Date

2022-07-01

Publish Date

2022-07-01

Page Start

29

Page End

35

Print ISSN

1110-2179

Online ISSN

2537-0979

Article File

EJMM_Volume 31_Issue 3_Pages 29-35.pdf

PDF . 345.8kB

Link

https://ejmm.journals.ekb.eg/article_247177.html

Detail API

https://ejmm.journals.ekb.eg/service?article_code=247177

Order

247,177

Type

New and original researches in the field of Microbiology.

Type Code

2,038

Publication Type

Journal

Publication Title

Egyptian Journal of Medical Microbiology

Publication Link

https://ejmm.journals.ekb.eg/

MainTitle

Bacterial Profile and Antibiotics Susceptibility Pattern of Pleural Effusion Isolates from Sohag University Hospital

Details

Type

Article

Created At

23 Jan 2023