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228625

Biosynthesized Silver Nanoparticles Induced Potential Antibacterial Activity

Article

Last updated: 23 Jan 2023

Subjects

-

Tags

Antimicrobial agents

Abstract

Background: Nanoparticles especially those synthesized biologically are promising in its applications in medical field. The nanoparticles synergic effect with common used antibiotics are the most targeted studies nowadays, in order to overcome the microbial antibiotic resistance problem. Objectives: To synthesize silver-nanoparticles (AgNPs) using desert plant Alhagi maurorum (am), and to examine their effects in improvement the antibiotics efficiency. Methodology: Extracellular silver-nanoparticles biosynthesis using Alhagi maurorum (desert plant). The synthesized silver-nanoparticles were characterized using UV-visible spectroscopy, scanning electron microscopy-energy dispersive spectroscopy (SEM-EDS), X–ray diffraction (XRD) and zeta potential in order to investigate their structural, and textural properties.Synergistic effect ofAgNPs plus antibiotics was also measured. Results: The UV-visible absorbance showed a strong intense peaks at 375 nm The XRD showed diffraction peaks  at 2θ=32.12°, 44.76°, 46.22° corresponding to the (122), (200), (231) which agreed with the quality value (JCPDS card No. 04-0783). SEM–EDS and XRD analysis confirmed the crystalline nature of silver-nanoparticles with spherical, oval and hexagonal in shape ranged from 37-79 nm in size. DLS analysis showed the size distribution of silver-nanoparticles with maximum intensity at 70 nm. The silver-nanoparticles showed considerable synergistic effect with different antibiotics. Conclusion: Silver can be reduced to nanoparticles by Alhagi maurorum extract. Considerable synergic effects were recorded by applying nanoparticles with diversified antibiotics on different pathogenic bacteria.

DOI

10.21608/ejmm.2022.228625

Keywords

Biosynthesis, silver nanoparticles, antibiotics, Synergistic, Alhagi maurorum

Authors

First Name

Khalid

Last Name

AbdelRehim

MiddleName

Abdalla Ali

Affiliation

Botany dept., Faculty of science, Sohag university - Sohag - Egypt

Email

khalidfp7@gmail.com

City

-

Orcid

-

First Name

Ahmed

Last Name

Mohamed

MiddleName

Mohamed Ali

Affiliation

Department of Biology, Preparatory Year, Shaqra University, Saudi Arabia.

Email

ahmedelymani22@gmail.com

City

-

Orcid

-

First Name

Sulaiman

Last Name

Al Yousef

MiddleName

A

Affiliation

Department of Clinical Laboratory Sciences, College Of Applied Medical Science, University of Hafr Albatin, P. O. Box 1803, Hafar Al Batin 31991, Saudi Arabia

Email

drsulaiman@uhb.edu.sa

City

-

Orcid

-

First Name

Alyousef

Last Name

Ali

MiddleName

-

Affiliation

MOH, Saudia Arabia

Email

manyousef@yahoo.com

City

-

Orcid

-

Volume

31

Article Issue

2

Related Issue

32749

Issue Date

2022-04-01

Receive Date

2022-03-04

Publish Date

2022-04-01

Page Start

49

Page End

55

Print ISSN

1110-2179

Online ISSN

2537-0979

Link

https://ejmm.journals.ekb.eg/article_228625.html

Detail API

https://ejmm.journals.ekb.eg/service?article_code=228625

Order

9

Type

New and original researches in the field of Microbiology.

Type Code

2,038

Publication Type

Journal

Publication Title

Egyptian Journal of Medical Microbiology

Publication Link

https://ejmm.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

23 Jan 2023