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228620

Serum Mannose Receptor as a Diagnostic Bio-Marker for Sepsis in ICU Patients in Ain Shams University Hospitals

Article

Last updated: 05 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Clinical microbiology

Abstract

Background: Sepsis is one of commonest complications that is associated with extended hospital stays. Making an early diagnosis is critical for improving its prognosis. Serum Mannose Receptor (sMR) is a biological biomarker which can be used in early diagnosis of sepsis. Objective: To investigate the value of sMR as a diagnostic biomarker for sepsis. Methodology: This study included 65 patients and 25 healthy individuals as control group. The patients' group was divided into two groups according to SIRS criteria. Blood samples from patients were collected for blood cultures. sMR levels were measured in patients and control groups. Results: The commonest isolated organism by blood culture was S. aureus. SMR levels among cases in the both groups were higher than controls with statistically significant difference. SMR could be used to discriminate cases in both groups with 97.5% sensitivity, 80.0% specificity. Conclusion: sMR is a promising biomarker in early predictor of sepsis.

DOI

10.21608/ejmm.2022.228620

Keywords

Sepsis, sMR

Authors

First Name

Fatma

Last Name

Shehata

MiddleName

Mohamady

Affiliation

Microbiology & Immunology, Faculty of medicine, Helwan University , Cairo, Egypt.

Email

fatmamohamady221@gmail.com

City

Zagazig

Orcid

-

First Name

Taghreed

Last Name

El-khashab

MiddleName

Hamed

Affiliation

Microbiology & Immunology, Faculty of medicine, Ain shams university, Cairo, Egypt.

Email

taghreedhtk@yahoo.com

City

Cairo

Orcid

-

First Name

Fager

Last Name

Hussein

MiddleName

Fathy

Affiliation

Microbiology & Immunology, Faculty of medicine, Ain shams university, Cairo, Egypt.

Email

fulla84-2007@hotmail.com

City

cairo

Orcid

-

First Name

Yasmin

Last Name

Ahmed

MiddleName

Mohamed

Affiliation

Microbiology &Immunology, Faculty of medicine, Ain shams university, Cairo, Egypt.

Email

yasmin.mostafa@hotmail.com

City

cairo

Orcid

0000-0002-1062-1738

Volume

31

Article Issue

2

Related Issue

32749

Issue Date

2022-04-01

Receive Date

2022-02-26

Publish Date

2022-04-01

Page Start

29

Page End

36

Print ISSN

1110-2179

Online ISSN

2537-0979

Article File

EJMM_Volume 31_Issue 2_Pages 29-36.pdf

PDF . 588.5kB

Link

https://ejmm.journals.ekb.eg/article_228620.html

Detail API

https://ejmm.journals.ekb.eg/service?article_code=228620

Order

6

Type

New and original researches in the field of Microbiology.

Type Code

2,038

Publication Type

Journal

Publication Title

Egyptian Journal of Medical Microbiology

Publication Link

https://ejmm.journals.ekb.eg/

MainTitle

Serum Mannose Receptor as a Diagnostic Bio-Marker for Sepsis in ICU Patients in Ain Shams University Hospitals

Details

Type

Article

Created At

23 Jan 2023