Beta
ManageSearchChatDiscover
211968

Correlation between Highly Sensitive C Reactive Protein and Development of Microvascular Complications of Type 2 Diabetes Mellitus

Article

Last updated: 28 Dec 2024

OverviewSimilar Items

Subjects

-

Tags

Diagnostics

Abstract

Background: Microvascular problems associated with type 2 diabetes mellitus (T2DM) are a leading source of morbidity and mortality in T2DM patients, thus the search for new biomarkers to identify and treat those at high risk is intensifying. Objective: This controlled cross-sectional study aimed to investigate whether there is a correlation between serum levels of highly sensitive C reactive protein (hsCRP) and development of microvascular complications in T2DM.Methodology:  Hundred and thirty-five subjects aged from 35 to 70 years were subdivided into 3 groups. Detailed clinical history was taken. Serum levels of hsCRP were estimated using Immune Turbidimetry. Results: Serum hsCRP levels were higher in group A than other studied groups. However, there was no statistically significant difference between group A and B(P=0.35). Serum hsCRP levels were significantly higher in patients with diabetic nephropathy than patients without nephropathy (P=0.016). The difference between serum hsCRP levels in patients with and without retinopathy and neuropathy was not significant (P=0.39 and P=0.53 respectively). Conclusion: Serum hsCRP can be used as a novel marker for diagnosis of microvascular complications in T2DM patients.
Abbreviations: (T2DM: Type 2 Diabetes Mellitus, hsCRP: highly sensitive C Reactive Protein, eGFR: Estimated Glomerular filteration Rate, BUN: Blood Urea Nitrogen, HbA1c: Glycosylated Hemoglobin). 

DOI

10.21608/ejmm.2022.211968

Keywords

T2DM, Microvascular complications, hsCRP

Authors

First Name

Amal

Last Name

Hassaan

MiddleName

-

Affiliation

Medical Microbiology and Immunology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt

Email

-

City

-

Orcid

-

First Name

Mohamed

Last Name

Abd El-Ghany

MiddleName

I.

Affiliation

Department of Internal medicine, Faculty of Medicine, Mansoura University, Mansoura, Egypt

Email

-

City

-

Orcid

-

First Name

Waleed

Last Name

Eldars

MiddleName

-

Affiliation

Department of Medical Microbiology and Immunology, Faculty of Medicine, Mansoura University, Mansoura, Egypt.

Email

wellydars@gmail.com

City

Mansoura

Orcid

0000-0002-4256-4977

First Name

Talat

Last Name

Othman

MiddleName

A.

Affiliation

Medical Microbiology and Immunology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt

Email

-

City

-

Orcid

-

Volume

31

Article Issue

1

Related Issue

29807

Issue Date

2022-01-01

Receive Date

2021-11-29

Publish Date

2022-01-01

Page Start

69

Page End

73

Print ISSN

1110-2179

Online ISSN

2537-0979

Article File

EJMM_Volume 31_Issue 1_Pages 69-73.pdf

PDF . 322.1kB

Link

https://ejmm.journals.ekb.eg/article_211968.html

Detail API

https://ejmm.journals.ekb.eg/service?article_code=211968

Order

10

Type

New and original researches in the field of Microbiology.

Type Code

2,038

Publication Type

Journal

Publication Title

Egyptian Journal of Medical Microbiology

Publication Link

https://ejmm.journals.ekb.eg/

MainTitle

Correlation between Highly Sensitive C Reactive Protein and Development of Microvascular Complications of Type 2 Diabetes Mellitus

Details

Type

Article

Created At

23 Jan 2023