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202158

Skin and Nasal Colonization with Methicillin Resistant Staphylococcus Aureus in Children with Atopic Dermatitis

Article

Last updated: 28 Dec 2024

OverviewSimilar Items

Subjects

-

Tags

Clinical microbiology

Abstract

Background: Atopic dermatitis (AD) is a chronic inflammatory skin disease with multifactorial etiologies, Staphylococcus aureus (S.aureus) and methicillin-resistant S.aureus (MRSA) that naturally colonize skin and nose are prevalent among children with AD. Objectives: was to determine the prevalence of S.aureus and MRSA colonization of skin lesions and nose of AD children. Methodology: 40 children diagnosed as AD from Dermatology Clinic of Najran Armed Forces Hospital, Saudi Arabia, were included in the study; separate swabs from skin lesions & nose of each AD patient were tested for S.aureus and MRSA colonization using the conventional culture based Vitek 2 system and the molecular BD Max MRSA XT assay. Results:  Using the conventional Vitek 2 system, the prevalence of skin and nasal colonization with S.aureus in AD patients were 25% and 30% respectively while skin and nasal colonization with MRSA were 7.5% and 7.5% respectively, the BD Max MRSA XT assay identified correctly S.aureus with overall 96 % sensitivity, 100 % specificity and 98 % diagnostic accuracy and identified 100 % of MRSA strains. Conclusion: The increase in prevalence of skin and nasal colonization with S.aureus and MRSA among AD children raises the concern about importance of the accurate and rapid molecular diagnostic techniques for preventing the potential risk of MRSA transmission

Keywords

atopic dermatitis, Methicillin resistant S.aureus, Vitek 2 system, BD Max assay

Authors

First Name

Tamer

Last Name

Mahmoud

MiddleName

Mohamed

Affiliation

Department of Medical Microbiology and Immunology, Faculty of Medicine, Sohag University

Email

tamermmm2000@yahoo.com

City

Sohag

Orcid

0000-0002-2668-1292

Volume

30

Article Issue

1

Related Issue

28170

Issue Date

2021-01-01

Receive Date

2020-10-18

Publish Date

2021-01-01

Page Start

39

Page End

44

Print ISSN

1110-2179

Online ISSN

2537-0979

Article File

EJMM_Volume 30_Issue 1_Pages 39-44.pdf

PDF . 338.8kB

Link

https://ejmm.journals.ekb.eg/article_202158.html

Detail API

https://ejmm.journals.ekb.eg/service?article_code=202158

Order

5

Type

New and original researches in the field of Microbiology.

Type Code

2,038

Publication Type

Journal

Publication Title

Egyptian Journal of Medical Microbiology

Publication Link

https://ejmm.journals.ekb.eg/

MainTitle

Skin and Nasal Colonization with Methicillin Resistant Staphylococcus Aureus in Children with Atopic Dermatitis

Details

Type

Article

Created At

23 Jan 2023