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197455

Non-dermatophyte Moulds as Emerging Pathogens of Onychomycosis among Patients Attending Mansoura University Hospital, Egypt

Article

Last updated: 23 Jan 2023

OverviewSimilar Items

Subjects

-

Tags

typing and identification

Abstract

Background: Onychomycosis is fungal infection of nails. Dermatophytes, Candida species, and non-dermatophyte moulds are the commonest causes of onychomycosis. Objectives: This study assessed the frequency of non-dermatophyte moulds causing onychomycosis and their antifungal susceptibility. Methodology: Our study included106 nail specimens obtained from patients attending Mansoura University Hospital from October 2019 to March 2021. All samples were examined by standard mycological methods. Results: Onychomycosis was detected in 86 nail specimens. Dermatophytes were isolated from 7 cases (6.6%), non-dermatophyte moulds from 62 cases (58.5%), Candida species from 17 cases (16.0%), and the remaining 20 cultures were negative for fungal growth. Among non-dermatophyte moulds the predominant isolates were Aspergillus fumigatus (25.5%), Aspergillus niger (17.9%), Aspergillus flavus (3.8%), Alternaria alternata (2.8%) and Penicillium species (2.8%). The non-dermatophyte moulds were highly sensitive to itraconazole and ketoconazole. Conclusion: Non-dermatophyte moulds are a common cause of onychomycosis that cause failure of therapy and should be considered in cases of onychomycosis.

DOI

10.21608/ejmm.2021.197455

Keywords

Onychomycosis, Non-dermatophyte moulds, Aspergillus infection

Authors

First Name

Rasha

Last Name

Elnagar

MiddleName

M.

Affiliation

Medical Microbiology and Immunology Department, Faculty of Medicine, Mansoura University, Dakahliya, Egypt

Email

drrasha_m@mans.edu.eg

City

Dakahliya

Orcid

0000-0002-5661-850X

First Name

Raghdaa

Last Name

Shrief

MiddleName

-

Affiliation

Medical Microbiology and Immunology Department, Faculty of Medicine, Damietta University, Damietta, Egypt

Email

-

City

-

Orcid

-

Volume

30

Article Issue

4

Related Issue

27919

Issue Date

2021-10-01

Receive Date

2021-09-07

Publish Date

2021-10-01

Page Start

55

Page End

64

Print ISSN

1110-2179

Online ISSN

2537-0979

Article File

EJMM_Volume 30_Issue 4_Pages 55-64.pdf

PDF . 1.3MB

Link

https://ejmm.journals.ekb.eg/article_197455.html

Detail API

https://ejmm.journals.ekb.eg/service?article_code=197455

Order

8

Type

New and original researches in the field of Microbiology.

Type Code

2,038

Publication Type

Journal

Publication Title

Egyptian Journal of Medical Microbiology

Publication Link

https://ejmm.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

23 Jan 2023