202353

Modification of Silk Fibroin and Gelatin-Chondroitin Sulfate Matrix with the Addition of Nanohydroxyapatite by Freeze-Drying Method for Tissue Engineering Application

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Last updated: 05 Jan 2025

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Abstract

Silk fibroin/gelatin-chondroitin sulfate/nanohydroxyapatite (SF/GE-CS/nHAp) composite scaffolds were prepared by freeze-drying approach. The prepared samples were investigated using BET, FTIR, SEM, and XRD studies. In addition, the investigation of the cell proliferation, adhesion and viability using MTT, DMEM solution, and mouse preosteoblast cell confirmed the cytocompatible nature of the composite scaffolds. These results showed that this composite could be a potential candidate for tissue engineering application.

DOI

10.18576/jpac/030308

Keywords

 Chondroitin sulfate, Nanohydroxyapatite, Nanocomposite scaffolds, gelatin, silk fibroin, tissue engineering

Authors

First Name

Mohammad

Last Name

Azadi

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Affiliation

Department of Chemistry, Payame Noor University, P. O. Box 19395-3697, Tehran, Iran.

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First Name

Zahra

Last Name

Shams Ghahfarokhi

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Affiliation

University of Birjand, Birjand, I. R. of Iran.

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First Name

Abbas

Last Name

Teimouri

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-

Affiliation

Department of Chemistry, Payame Noor University, P. O. Box 19395-3697, Tehran, Iran.

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Volume

3

Article Issue

2

Related Issue

28515

Issue Date

2017-09-01

Receive Date

2021-10-31

Publish Date

2017-09-01

Page Start

88

Page End

93

Online ISSN

2357-0210

Link

https://jpac.journals.ekb.eg/article_202353.html

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https://jpac.journals.ekb.eg/service?article_code=202353

Order

202,353

Type

Original Article

Type Code

2,018

Publication Type

Journal

Publication Title

Journal of Pharmaceutical and Applied Chemistry

Publication Link

https://jpac.journals.ekb.eg/

MainTitle

Modification of Silk Fibroin and Gelatin-Chondroitin Sulfate Matrix with the Addition of Nanohydroxyapatite by Freeze-Drying Method for Tissue Engineering Application

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Article

Created At

23 Jan 2023