Glucose exists in various forms in solution. At any given time, glucose is present in a 6-membered ring (pyranose) and 5-membered ring (furanose), this second can also be important in biologically domaine. Glucofuranose and glucopyranose isomers could be efficiently synthesized using small amaount of maghnite-H+ (clay fin 2 % wt) in alkali medium under microwave irradiation. A representative microwave synthesized of glucose isomers was characterized using Fourier Transform Infrared Spectroscopy. Our present investigation showed that the different forms of glucose such as glucofuranose and glucopyranose newly synthesized with green catalyst called maghnite-H+(Algerian MMT) in aqueous medium are many more clair in chemicals properties and yield than these synthetezed by enzymatic way . Under microwave conditions oxygen removal from the reaction vessel was not required and the products was obtained in high yield using very small amount of clay.