The study aimed at investigating the effectiveness of mobile learning service SMS on enhancing mobile learning acceptance among Al-Aqsa University students. For the study objectives to be fulfilled, the researcher used experimental and descriptive approaches, analyzing the content of an instructional technology course so as to access the instructional technology concepts list including (37)concepts. The researcher also designed the study instrument (mobile learning acceptance measure). The sample of the study consisted of (140) students randomly selected from the whole population (1378) students. Data analysis revealed that there was an effective impact of the mobile learning SMS service on enhancing mobile learning acceptance among Al-Aqsa University students. Moreover, the effectiveness of mobile learning SMS service use on enhancing mobile learning acceptance among the Al-Aqsa University students exceeded 80%.