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179121

The effect of anaemia and malnutrition on the healing of diabetic foot wound

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Last updated: 28 Dec 2024

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Abstract

Background: Anaemia is a common problem in surgical patient, and it is an independent risk factor for blood transfusion,  peri-operative  infection,  mortality  and a longer in-patient stay. Diabetic  foot wound  results  from  the  interaction  of  several  contributory  factors,  the most important of which is neuropathy. With respect to the management of acute Charcot neuroarthropathy in diabetics, patients with diabetic foot wounds suffer from chronic inflammation, repeated infection, often undergo several invasive or operative treatments, and can have a protracted hospital stay. We hypothesised  that, for these  reasons, many patients with diabetic foot wound may suffer anaemia, require blood transfusion and suffer from poor nutrition. Aim  of the work: Anaemia and nutritional status assessment as they affect the healing in patients presenting with diabetic foot wounds. Patients and methods:  Two observational  studies were undertaken. Initially a retrospective series  of  20  patients  with  diabetic  foot  wounds.  Patient  demographics,  clinical  details, transfusion status and in-patient laboratory haemoglobin values (Hb) were recorded. In a prospective series of 33 patients, laboratory markers and nutritional status were assessed. Infection was excluded and managed appropriately by antibiotics and surgically by wound debridement or amputation. Other factors affecting wound healing were excluded as peripheral arterial diseases or debilitating diseases as renal failure. Results:  In the retrospective series, 17 patients (85%) were anaemic (100%  females) with average haemoglobin of5g  (SD 2.4) below the lower limit of normal for the sex ofthe patients. Ten patients  (50%)  were  transfused.  The  average  trigger  haemoglobin  index  was  8.5 gldl (SD 0.8). Patients  who were transfused  had lower haemoglobin  on admission  (p  = 0.0016). Overall, at discharge, most of the patients were anaemic (92%). In the prospective  series on admission,  27 patients  (82%)  were anaemic,  also  anaemic  patients had a higher CRP  and lower albumin level. 17 patients (52%) had been scored to be undernourished. Clinical follow up with appropriate dressing ofthe wounds  and calculating the healing rate was observed. Conclusion: Usually  anaemia as well as poor nutrition is the normal event and affecting the healing of diabetic wounds. Multidisciplinary review should be undertaken in all patients.

DOI

10.21608/asjs.2014.179121

Authors

First Name

Ahmed

Last Name

Osmane

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Affiliation

Department of Vascular Surgery, Alexandria University, Alexandria, Egypt.

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Orcid

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First Name

Naguib

Last Name

ElAskari

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Affiliation

Department of Vascular Surgery, Alexandria University, Alexandria, Egypt.

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Volume

7

Article Issue

2

Related Issue

25658

Issue Date

2014-07-01

Receive Date

2021-06-21

Publish Date

2014-07-01

Page Start

357

Page End

362

Print ISSN

2090-7249

Online ISSN

3009-7509

Link

https://asjs.journals.ekb.eg/article_179121.html

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https://asjs.journals.ekb.eg/service?article_code=179121

Order

17

Type

Original Article

Type Code

1,943

Publication Type

Journal

Publication Title

Ain Shams Journal of Surgery

Publication Link

https://asjs.journals.ekb.eg/

MainTitle

The effect of anaemia and malnutrition on the healing of diabetic foot wound

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Article

Created At

23 Jan 2023