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179596

Role of pre-operative gonadotropin in orchidopexy

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Last updated: 05 Jan 2025

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Abstract

Background: To evaluate the role of human chorionic gonadotropin  (HCG) in cryptorchid boys regarding testis position and size in treatment of palpable undescended testis (UDT). Patients and methods:  One hundred children presented with unilateral palpable UDT were studied in the period from May 2007 to May 2010. Their ages ranged from2-12 years with mean age 6.4 years SD ±2.1 and were divided into two equal groups: Group A- {control group) in which surgical orchidopexy was done without preoperative hormonal  preparation and Group B- {studied group) in which the patients received preoperative intramuscularinjection of HCG 30-50IU(Pregnyl) per kilogram ofbodyweight, two times a week for five succeeding weeks. The patients were subjected to clinical examination, laboratoryinvestigationsincluding testosterone level pre- and post- HCG therapy, ultrasound (UIS) and color Doppler ultrasound (CDUS). The results were assessed clinically, hormonal level, and CDUS  Standard orchidopexy was done in all cases. Both groups were assessed in teims  of testicular size and vascularity by CDUS  The mean basal and post-HCG stimulation  serum testosterone level were also compared in both groups. Both groups were also followed up postoperatively, clinically and by UIS Results:   found sizable testis, long cord withgood vascularity, easily dissectible associated hernial sac and more capacious scrotum with good post-operative results in group B patients. Conclusion: Preoperative HCG treatment is a safe effective tool to increase testicular size and viability which improve the results of orchiopexy

DOI

10.21608/asjs.2014.179596

Keywords

Undescended testis, orchiopexy, human chorionic gonadotropin(HCG

Authors

First Name

El-sayedH.

Last Name

Abdallah

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Affiliation

Departments of General Surgery (Pediatric Surgery Unit), Al-Azhar University

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Orcid

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First Name

Mohammed

Last Name

A.Abdelkhalekb

MiddleName

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Affiliation

Departments of Urology, Al-Azhar University

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City

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Orcid

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First Name

Amr

Last Name

A.Mostafa

MiddleName

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Affiliation

Department of Radiology, Al-Azhar University

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Volume

7

Article Issue

1

Related Issue

25657

Issue Date

2014-01-01

Receive Date

2021-06-23

Publish Date

2014-01-01

Page Start

1

Page End

6

Print ISSN

2090-7249

Online ISSN

3009-7509

Link

https://asjs.journals.ekb.eg/article_179596.html

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https://asjs.journals.ekb.eg/service?article_code=179596

Order

23

Type

Original Article

Type Code

1,943

Publication Type

Journal

Publication Title

Ain Shams Journal of Surgery

Publication Link

https://asjs.journals.ekb.eg/

MainTitle

Role of pre-operative gonadotropin in orchidopexy

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Article

Created At

23 Jan 2023