Background:  Liver resection  has  been increasingly  performed  over  the last  2 decades worldwide because of improved postoperative outcomes and evidence that this approach offers the only chance of cure in many patients. Technical innovations  have mainly  focused on minimizing  bleeding  during transection of the hepatic parenchyma because excessive hemorrhage and the need  for blood transfusion are associated with increased postoperative morbidity and mortality Liver resection is still a high risk procedure because of difficulties in preoperative assessment of functional liver  volume and severity  of co-morbidity, complexities  of surgical procedures for preserving enough  functional liver and preventing injury  to mcyor vessels in the remnant liver. Although  zero mortality  can be achieved  during a limited  period in some centers,  the postoperative mortality in most studies is between 1%-5%, even in patients with normal liver background. Postoperative  death can be attributed  to liver  failure, infection  in surgical  site, bleeding from esophageal varices, bile leakage, and extrahepatic diseases. Methods: In this study, we classified  postoperative  complications  into  major and  minor ones according to their  fatal potential. We hypothesized  that improved  surgical technique can decrease surgical complications, while patient selection and careful perioperative management are important to prevent mcyor complications.  Randomized  collection of twenty nine patients underwent partial hepatectomy for different indications. Analysis of every case has been done, retrospectively Results:   In  this  study, the most  common indication  of liver  resection  was liver  tumors accounting  for 82.7% of cases, primary hepatic malignancy accounting  for 75.8%. Extension of liver resection was a predictor  factor of complication. Major complications  were observed with rate  of 29. 4% in  patients  who were subjected  to major  resections.  The most  common complication  was liver  decompensation  accounting   for 24.1%,  was  observed  in  cirrhotic patients. Conclusion: Our  findings  demonstrate  that liver  resection  can  be  performed  with  low mortality and acceptable morbidity rates. Surgical complications can be reduced by employing meticulous  surgical technique and,  whenever indicated,  vascular exclusion. In addition,  use of vaccine against HBV eventually decreases the incidence,  especially in endemic areas, and prevents the development of cirrhosis, which predisposes to hepatocellular carcinoma and liver decompensation after rersection.