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179206

Outcome after hepatectomy versus percutaneous radiofrequency ablation for treatment of solitary hepatocellular carcinoma in Childs A cirrhotic patients

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Last updated: 23 Jan 2023

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Abstract

Aim: Is to compare the short-term outcome of hepatic resection and radiofrequency ablation (RFA) in two groups of patients with a solitary hepatocellular carcinoma (HCC) less than 5 em in Childs A cirrhotic patients. Patients and methods: The study comprised 60 patients; 52 (86.7%) males and 8 (13.3%) females,  with  mean  age  45.2±9.6,  range  26-67  years.  The  patients  were randomized  into 2 groups: Resection group (n=28 patients) assigned to undergo hepatic resection and radiofrequency group (n= 32 patients) assigned to undergo RFA. The morbidity; hospital stay; overall survival; disease-free survival; psychological and physical welfare of the patients were assessed during the follow up period. Results:  There  was  non-significant  difference  (P >0.05)  in  both  groups  as  regards  the morbidity (21.4% in resection group versus 15.6% in RFA group).The mean hospital stay was 7±2.9 in resection group and 1±1.2 in RFA group; with a significant shorter stay (P<0.001) in  RFA group.  Patients  included  in  RFA group  showed  significantly  increased  scores  of psychological and physical welfare compared to resection group (P<0.001). Subgroup analysis showed non significant difference between both groups as regards the 2 years overall survival &  recurrence-free  survival in tumours  less than 3cm.On  the other  hand,  surgical resection was superior to RFA for 2 years overall survival & the recurrence-free survival in subgroup analyses for lesions > 3cm, <5cm. Conclusion: In patients with ChildA cirrhosis with solitaryHCC  >3cm, RFAprovided results with non-significant difference to surgical resection with the advantages of being less invasive, shorter hospital stay, and better quality of life. While in tumours between 3 and 5 em, surgical resection was superior to RFA having better overall survival and tumour-free recurrence

DOI

10.21608/asjs.2012.179206

Keywords

Radiofrequency ablation, Hepatic Resection, Hepatocellular carcinoma

Authors

First Name

Gamal

Last Name

Saleh

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Affiliation

Department of General Surgery, Benha University Hospital, Egypt.

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First Name

Mostafa

Last Name

El-Sayed

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Affiliation

Department of General Surgery, Benha University Hospital, Egypt

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First Name

George A.

Last Name

Nashed

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Affiliation

Department of General Surgery, Cairo University Hospital, Egypt.

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First Name

Magdy

Last Name

Gad

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Affiliation

Department of Tropical Medicine, Benha University Hospital, Egypt.

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First Name

Mohamed S.

Last Name

Abdelbary

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Affiliation

Department of Tropical Medicine, Cairo University Hospital, Egypt.

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Volume

6

Article Issue

1

Related Issue

25656

Issue Date

2013-01-01

Receive Date

2021-06-22

Publish Date

2012-10-01

Page Start

1

Page End

12

Print ISSN

2090-7249

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https://asjs.journals.ekb.eg/article_179206.html

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Original Article

Type Code

1,943

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Journal

Publication Title

Ain Shams Journal of Surgery

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https://asjs.journals.ekb.eg/

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Created At

23 Jan 2023