Background: The obvious goal of therapy in choledocholithiasis is to achieve ductal clearance with the fewest number of interventions, lowest cost and least morbidity. Until now no agreement about the ideal approach for management of stone common bile duct associated with gall bladder stone that may be achieved cu"ently according to a two-step-protocol (endoscopic sphincterotomy associated with laparoscopic cholecystectomy) or by a one-step laparoscopic procedure, including exploration of the CBD and cholecystectomy. The aim of this study is to evaluate both procedures and to determine the prognostic factors to prefer either of both. Patients and methods: A prospective study included 44 patients treated for gallbladderICED stones in the period from October 2008 through December 2010 were divided into two groups, group A treated  with Lap first (by the first two authors#) and group B treated with ERCP first (was treated with the second two authors*). The obtained results were compared with each other; the mean follow-up period was 6±1.3 months (range; 4-8 months). Results: Total operative time was shorter for LC+LCBDE. The incidence of postoperative complications such as cholangitis  and pancreatitis are common in group B versus group A. Regarding the success rate and conversion rate; in group A two cases were converted to open surgery and one case to ERCP, versus two cases in group B (due to difficult cannulation, so they were converted to lap surgery) and one case due to impacted large stone more than 2 em that was converted  to open surgery. Late complications are bile leakage in group A, versus three  cases  in group  B in the  form  of  mild  pancreatitis and  cholangitis and  bleeding. Conclusions: LC+LCBDE and ERCPIS+LC were highly effective in detecting and removing common bile duct stones and were equivalent in overall cost and patient acceptance. LF approach to gallbladder/CBD stones is safe and feasible. It may allow the majority of surgeons to avoid excessively difficult/dangerous surgical procedures as well as unnecessary ERCPs in most cases.