Background: Perforated peptic ulcer is a common surgical emergency. Its classic treatment is the mid-line laparotomy. However, laparoscopic treatment has been shown to be reliable. Few studies have evaluated its overall utility. The aim of this study is to assess the efficacy of laparoscopy in perforated peptic ulcer repair. Patients and methods: The study included 18 patients presented by perforated peptic ulcer between July 2009 and December 2011. They were submitted to laparoscopic omental patch repair with thorough peritoneal wash. Patients' demographics, diagnostic techniques, management, and outcome were evaluated. Results: The mean age was 35.6 years. Male to female ratio was 14:4. The mean duration of symptoms was 18 hours. The perforation  was diagnosed by plain X-ray of the abdomen in erect position in 15 patients and by abdominal CT scan in 3 patients.The laparoscopic repair of the perforation  was successful  in 16 patients while in 2 patients mid-line laparotomy  was needed for proper control of the severe intra-abdominal sepsis. The mean operative time was 90 minutes. Post-operatively, the VAS score ranged between 3 and 6 with a mean of 3.5 in the first post-operative day. Narcotics were needed for a mean of 1.5 days. All the patients tolerated soft diet on the 3rd post-operative day and full diet on the 4th post-operative day. The mean duration of hospital stay was 4.5 days. One patient developed post-operative intra-abdominal collection  that was treated by ultrasound  guided drainage. One patient developed umbilical port  site wound  infection. No chest  infection, prolonged  ileus,  leakage, or mortality was encountered in the study. Conclusion: Laparoscopic repair of perforated peptic ulcer is a safe and reliable technique with accepted morbidity and mortality rates and all the advantages of the minimally  invasive surgery.