Background: The rehabilitation program is usually the cornerstone post-rotator cuff surgery. The role of the nurses post-surgery includes physical assessment, pain management, and education to the patient on the safe compensatory strategies to optimize functional abilities. Aim: evaluate the effect of a nursing rehabilitation program on shoulder joint range of motion and functional abilities for patients post rotator cuff surgery. Design: A quasi-experimental research design was utilized. Setting: This study was carried out at the Hadara Orthopedic and Traumatology University Hospital, Alexandria. Subjects: A convenience sample of sixty adult patients were scheduled for rotator cuff surgery. Tools: Tool I: Rotator cuff surgery patient's assessment: structured interview schedule. Tool II: Modified visual analog scale. Tool III: Range of motion of the affected shoulder. Tool IV: Muscle strength scale of the affected shoulder. Tool V: Functional abilities of the upper limb. Results: The results showed that the control group had unsatisfactory knowledge pre, immediately & two months post-rehabilitation program (96.7%,96.7%,83.3% respectively) compared to (83.3%, 63.3%, 40% respectively) of patients of the study group, with the statistically significant difference among them (p0=(0.001*). Moreover, there was a statistically significant difference between patients of both studied groups regarding the range of motion, muscle strength, and overall functional abilities of the affected shoulder two months post-rehabilitation program. Conclusion: A nursing rehabilitation program has been proven to give a positive result to patients in relation to shoulder joint range of motion and functional abilities post rotator cuff surgery. Recommendation: Replication of the study on large probability sampling.