A field experiment was conducted during two consecutive seasons of 2017/2018 and 2018/2019 in Agricultural Farm of Sids Agricultural Research Station, ARC, Beni-Suef Governorate, Egypt. The experiment aims to compare the effects of some planting methods (flat, ridges and raised bed) and wheat varieties, i.e., Misr 2 and Sids 14 under different nitrogen fertilization rates (0.0, 120 and 180 kg ha-1 ) and its effect on wheat crop growth parameters, yield and yield components and nutrient status of wheat (Triticum aestivium L.). The design of the experiment was split-split plot in completely randomized blocks in four replicates. The results expressed that Misr 2 surpassed Sids 14 variety on growth parameters, yield and its components and N, P and K uptake, except number of spikes m-2 . Raised bed method exhibited the highest values of growth parameters, yield and yield components and NPK uptake, except 1000-grain weight. Increasing nitrogen fertilizer rates up to 180 kg ha-1 were significantly increased all studied growth parameters, yield and its components as well as nutrient content and uptake. The results of the interaction between treatment show that cultivation Misr 2 variety on raised bed under application of 180 kg N ha-1 gave highest wheat productivity.