Twenty F1 grain sorghum crosses, their parents (four sterile female tester and five male lines) and one commercial check hybrid (Shandaweel-305) were evaluated for yield and five other characters in 2019 and 2020 seasons at Arab El-Awamer Station, Assiut, Egypt. The obtained data showed highly significant differences between genotypes and their partition, crosses, parents and crosses vs parents for all studied traits except for parents for grain yield/plant and crosses vs parents for panicle width, 1000-grain weight and grain yield/plant. Meanwhile, mean squares due to lines, testers and their interaction were significant or highly significant for all traits except for 1000- grain weight of lines. Most of the crosses were earlier and had higher grain yield/plant than their parents. The best parents for general combining ability effects were BSH-1 and ICSR-89016 for grain yield/plant. Thus, these two lines can be used in sorghum breeding program for improving grain yield. Moreover, the best crosses for specific combining ability were (ICSR-89031 XAsh-1 and ICSR-89031 X Ash-11) for grain yield/plant. Two crosses(ICSR-89016 X Ash-3 and ICSR-89016 X Ash-11) out-yielded the check. The best crosses for heterosis relative to better parent were (ICSR-89016 X Ash-1 and ICSR-89031 X Ash-3(.