The planting of hybrid cultivars in cantaloupe played a great role in the improvement of production and quality of the crop. Thus, this study was conducted during the period from 2016 to 2018 for improving the productivity and fruit quality of cantaloupe crop under low tunnels in the winter seasons by enhancing the earliness and average fruit weight through crossing between five parental selected cantaloupe recombinant inbred lines (RILs) from a previous breeding program to produce 20 F1 (10 crosses and 10 reciprocal F1 crosses) hybrids. These 20 hybrids, their five parental RILs and two commercial F1 hybrids (Yathreb 7 and Gold Stone) were used as controls for determining the best hybrid suitable to grow under low tunnels in the winter seasons. Besides, some genetic determinations of early yield and average fruit weight were done to identify the genetic nature of these two traits under low tunnels in the winter seasons. Results confirmed that the best hybrid for planting under low tunnel was RIL G16 × RIL G38 which ranked first and fifth in total and early yield, respectively, and had high fruit quality. The highest value of mid and better parents heteosis were 143.79 and 120.00% in hybrids RIL G42 × RIL G4 and RIL G42 × RIL G16, respectively for early yield. Also, the highest value of mid parent heterosis was 68.63% in hybrid RIL G16 × RIL G38 for average fruit weight, but non-significant heterobeltiosis (heterosis relative to the better parent) was shown in all hybrids for the same trait. The general combining ability effects of the parents were agreed with the specific combining ability effects of the hybrids for early yield and average fruit weight traits. Likewise, the coefficient of variance was 7.94 and 10.01% for average fruit weight and early yield, respectively. The, estimated genotypic coefficient of variance (GCV %) vs. phenotypic one (PCV %) were 19.658 vs. 21.201% for average fruit weight and 34.129 vs. 35.565% for early yield. Small difference were observed between GCV and PCV in average fruit weight and early yield, indicating the importance of the genetic effects in controlling the inheritance of these two traits. In addition, broad sense heritability (h2b) was high (85.975 and 92.086) for average fruit weight and early yield, respectively.So, the high value of (h2b) indicating that the cantaloupe can be improved through selection based on phenotypic observation. Finally, a highly positive correlation (r = 0.93**) was detected between early yield and flowering in cantaloupe RILs, suggesting that the selection of early flowering could be associated with great early yield and this could save effort for the melon breeders.