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191565

DIRECT AND TRANSPLACENTAL INDUCTION OF TUMOR IN RATS AFTER SINGIE EXPOSURE TO DIFLUBENZURON INSECTICIDE

Article

Last updated: 05 Jan 2025

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Abstract

The oral LD50 of Diflubenzuron was determined in Agoza strain albino rats, survived animals were left and slaughtered after eleven months. Post mortem and histopatholo gical examination revealed the p < /strong>resence of squamous cell carcinoma in the stomach and polygonal cell carcinoma of the lungs. The offspring from mothers administered the LD50 dose at the 18th day of pregnancy developed hep < /strong>atocellular carcinoma which metastasis in their lungs. Detection, tissue distribution and evidence of transplac ental transmission of diflubenzuron were investigated by TLC, sp < /strong>ectrophotometric and Infra-red spectrscopic techniques.

DOI

10.21608/avmj.1982.191565

Authors

First Name

F.E.

Last Name

SHAABAN

MiddleName

-

Affiliation

Dept. of Medicine, Faculty of Vet. Med., Zagazig University

Email

-

City

-

Orcid

-

First Name

SOMMAYA,

Last Name

H.

MiddleName

-

Affiliation

Dept. of Medicine, Faculty of Vet. Med., Zagazig University

Email

-

City

-

Orcid

-

First Name

EL. SAYED

Last Name

M.H.

MiddleName

-

Affiliation

Dept. of Medicine, Faculty of Vet. Med., Zagazig University

Email

-

City

-

Orcid

-

First Name

KADRI, A.

Last Name

MOUSTAFA

MiddleName

-

Affiliation

Dept. of Medicine, Faculty of Vet. Med., Zagazig University

Email

-

City

-

Orcid

-

First Name

A.H.

Last Name

ABU HADEED

MiddleName

-

Affiliation

Dept. of Medicine, Faculty of Vet. Med., Zagazig University

Email

-

City

-

Orcid

-

Volume

9

Article Issue

17.18

Related Issue

27211

Issue Date

1982-01-01

Receive Date

1980-12-14

Publish Date

1982-01-01

Page Start

153

Page End

159

Print ISSN

1012-5973

Online ISSN

2314-5226

Article File

AVMJ_Volume 9_Issue 17.18_Pages 153-159.pdf

PDF . 3.8MB

Link

https://avmj.journals.ekb.eg/article_191565.html

Detail API

https://avmj.journals.ekb.eg/service?article_code=191565

Order

25

Type

Research article

Type Code

1,840

Publication Type

Journal

Publication Title

Assiut Veterinary Medical Journal

Publication Link

https://avmj.journals.ekb.eg/

MainTitle

DIRECT AND TRANSPLACENTAL INDUCTION OF TUMOR IN RATS AFTER SINGIE EXPOSURE TO DIFLUBENZURON INSECTICIDE

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Article

Created At

23 Jan 2023