Red and white blood cells picture was studied in sheep orally dosed daily with 2 mg/kg. Bwt. sodium fluoride and following calcium and aluminum treatment of such cases. Total red blood cell count was insignificantly affected while significant (P/_0.05) changes were recor ded for haemoglobin content and packed cell volume. Total white blood cells count was significantly varied. The differential leucocytic count was altered following toxication with sodium fluoride and after calcium therapy (calphon) of toxic cases.