Serum hemoglobin as well as some other serum parameters, were determined in 40 healthy Egyptian Goats. Mean values of serum hemoglobin was 120.78+5.95 mg/100 ml; also the values of serum • aspartat amino transferase; serum total bilirubin; serum total protein; serum potassium asnd serum chloride were estimated. In vitro hemolysis was made; the effect of in-vitro hemolysis was studied. A significant adultrations of values of serum hemoglobin; serum spartat amino transferase; serum potassium were marked with silght and severe degree of hemolysis, while other parameters were less or not affected.