Three injectable fasciolcide drugs Bilevon 4%, Dovenix 25% and Flukanide 7.5% solutions were used in this study to evaluate their efficiency on Fasciola infested buffaloes. The same drugs were also tried on three groups apparently healthy, parasitic free buffaloe-calves in order to throw some light on their effects on liver and kidney functions. The three remedies used proved to be equally efficient on mature liver fluke.
Biochemical analysis of blood components showed insignificant changes between these drugs after one, 2,7 and 14 days from injection in healthy non infected buffaloe-calves.
It could be concluded that Bilevon 4%, Dovenix 25% and Flukanide 7.5% could be safely used as fasciolicides without any harmful effect on parenchymatous organs as liver and kidney.