An acute infection characterized by septicaemia and daily mortality of about 4% six-months-old, Hubbard chickens was recorded during "1982" at El-Wadi El-Gadid, Poultry Farm. Bacteriological examinations of dead birds revealed the recovery of "14" E.coli isolates belonging to "3" serotypes. Experimental infections proved that the isolates were pathogenic to different ages of chickens.
The isolated strains were sensitive to Nitrofurantion, Chloramphenicol and Neomycin. According to the previous result Furaltadone and Chlora mphenicol were used in drinking water for 7 days to control the infection.