A clinical trial involved four severely dehydrated calves and nine modera tely dehydrated calves. Both were affected with acute neonatal diarrho ea AMER; HASSAAN; EL-SEBAIE; BAYOUMI and IBRAHIM (1983). All calves were given a combinations of prepared oral electrolytes, parenter al balanced electrolytes, to correct dehydration and maintain hydration, in conjunction with the antibiotic of choice at adequate dose levels. The amounts given calculated according to the severity of dehydration. The intravenous route of administration in this trial gave quick and encouraging results. Calves were starved for 18-24 hours, not allowed any milk. Both the treatment and control of diarrhoea in the affected calves are difficult and frustrating because often the cause of diarrhoea can not be determined quickly and accurately, nevertheless following this infusion therapy regimen clinical, spectacular results were achieved.