A total of 1038 samples were 'taken from the digestive and respira tory organs of 352 dead chickens collected from different farms in Kena. They were examined for mycotic flora, 228 Aspergillus species (Afumigatus, A.flavus, A.niger) as well as 306 other moulds belonging to Mucor, Rhizopus, Paecilomyces, Penicillium and Sp < /span>oro trichum were recovered. In addition to a 23 yeast species (Rhodotrula and Sacchromyces) were isolated from the examined organs. On the other hand 60 Aspergillus species A. fumigatus, A.flavus, A.niger and A. flavipes) and 33 other mould species (Mucor, Rhizopus, Sporo trichum and Paecilomyces), together with 4 yeast species belonging to Geotrichum and Rhodotrula were isolated from feed, drinking water, egg-shell, hatcharies and brooder rooms. Pathogenicity of some isolates were studied in 3 days-old Fayoumi chicks, clinical signs, mortality and P.M. lesions were recorded. The effect of drugs on some isolates was studied in vitro. Garlic and thiobenzole were more effective than mycostatin and copper sulphate.