The buffaloes of first to third parity were injected during the last month of gestation by 150 mg sodium selenite in a rate of two doses with one week interval. Periparturient blood samples were taken to assay serum FSH, LH and prolactin levels. The levels of these hormones were significantly increased after birth when com pared with the non-treated cases. It is concluded that selenium can be considered as an influencial element in restoration of cyclic ovarian function after parturition in Egyptian buffaloes.