Twenty sheep were included in this study, 12 of which were suffering from rumen acidosis while the rest served as control.
Blood samples were collected from normal as well as diseased sheep for biochemical analysis. In addition to that, specimens from liver, kidneys, lungs and spleen were taken from two affected cases which were emergancy slaughtered and one died ase for histopathological examination. The obtained results were as follows:
- Biochemically, acidosis in sheep was accompained by sig nificant increase in serum bilirubin, creatinine, urea nitrogen, serum transaminases, lactic dehydrogenase and serum potasium. On contrast blood glucose, serum alkaline phosphatase and serum sodium were significantly decreased.
- Histopathological studies revealed various degenerative changes were occurred in liver and kidneys. Lung Dedema and emphysema, besides to lymphoid hyperplasia and haemosiderosis in spleen were also observed.
- From this study, it was concluded that rumen acidosis has an adverse effect on blood metabolites and vital organs as revealed from blood changes that was also confirmed histopatho logically.