The present investigation recorded the levels of the industrial pollutant (fluorine) and the related elements (phosphorus, calcium, sodium and potassium) in both macro and microenveronment of cattle in ten' areas at Assiut governorate. The results indicated a significant elevation in fluoride levels in water, feedstuffs and meat in three investigated areas (Manqubad, Abnoub and El-Wasta). High levels of calcium and phosphours were recorded in kidney. Also sodium and potassium levels in the kidney showed the same behaviour. A lower levels of both calcium and phosphorus were recorded in muscles and liver of cattles in the three affected areas (Manqubad, Abnoub and El-Wasta).