Laryngotomy was performed on 24 normal adult donkeys. The suture closure of the laryngotomy wound was performed in 12 donkeys, while the surgical site was left to heal by second intention in 12 donkeys. All animals were clinically observed. The surgical site examined daily in all animals. Three animals of each group were sacrificed along different periods postoperatively (1, 3, 5 and 8 weeks). Postmortem and histopatho logical examinations were recorded. The result revealed that suturing of the laryngotomy incision is recommended because it prevent that complications which occure after keeping the laryngotomy incision without suture.