An outbreak in broiler chickens with 4.8% mortality
caused by Staphlococcus aureus (S. aureus) and Klesiella peneumoniae (K. pneumoniae) was encountered by the authors. The clinical signs of the infected broiler ckickens were sligh depression and bluish discolouration of the head region. The * macroscopic lesions were oedematous haemorrhagic exudate of the subcutaneous* (s/c) tissue in the head region and vascular congestion of the internal organs. Bacteriological cultures of sp < /strong>ecimens on blood agar and mannitol salt agar as well as biochemical and biological characters, revealed S. aureus and K. pneumoniae. 8% and 2% mortalities were noticed in the s/c injected chicks with s. aureus and K. p < /strong>neumoniae, respectively. - On the other hand 12% mortality, was rep < /strong>orted in chicks injected s/c with both organisms simultaneously. The clinical observations, of exp < /strong>erimental infection were similar to a great extent to those of natural infection. In vitro drug sensitivity, S, aureus was highly sensitive to p < /strong>enicillin, amp < /strong>icillin and enroflocin. K. pneumoniae was highly sensitive to enroflocin, flumequine and oxanilic acid.' field trial of simultaneous, injection with penicillin strep < /strong>tomycin gave a good results for controlling the outbreak..