A total of 2406 cattle and 794 sheep blood samples were examined serologically for tube agglutination test (TAT). The reactor samples (33 cattle and 20 sheep) were subjected for Rose Bengal plate test (RBPT), buffered acidified plate test (BAPAT) and coombs tests. The last test was the most sensitive one, then BAPAT, while RBPT was the least sensitive one. The superiority of coombs sensitivity is more evident in case of the 1st titre TAT reactor (1/10). So, it is advisable that coombs test must be essentially involved in brucella profile serological tests as a high sensitive one.