Ten apparantly healthy, lactating dairy buffaloes (relatively similar in age, weight and stage of lactation) at the farm of Faculty of Veterinary Medicine, Suez Canal University were used for each drug. They were injected with Mastalone intramammary, sulfadimidine 33.3% I/V, panteramycin I/M, streptopencid I/M and terramycin tablets intrauterine. The obtained results reveal that the withdrawal period were 156 h and 132 h for quarter and
composite milk, respectively, 108 h, 60 h, 120 h and 72 h for the drugs used, respectively. About 60% of treated buffaloes produced antibiotic residues in their milk beyond the end of recommended withdrawal times. A good agreement (92.99 %) was detected between the Delvotest-P and BR test.