SUMMARY A sublethal dose of crude venom extracted from the Jelly fish Eutonina indicans was injected intraperitoneally to mice (1.78 mg/20 gm b.w.). The percentages of blood serum ( A1, A2, B, V, ) globulins and albumin were determined. Also, the levels of liver proteins, glycogen, total lipid, TBARS, transaminases (S. GOT & S. GPT) alkaline and acid phosphatases were determined. After 24 hours of treatment, the crude venom induced
EFFECT OF JELLY FISH VENOM ON LIVER FUNCTION
insignificant (P >0.05) changes of Q1, A2, B, v, globulins and albumiin percentages, on the other hand, this extracted crude venom induced a significant (P<0.001) increase in the liver total proteins and glycogen levels, while the levels of lipid, TBARS, transaminases (S. GOT & S. GPT) alkaline and acid phosphatases activities showed in-significant (P>0.05) changes. This extracted crude venom was p < /strong>erformed on Nicolet apparatus cod 710 FT-IR spectrometer which predict that the structure of the venom may be aliphatic compound. The biological effect of this extracted venom may be attributed to the direct effect of crude venom bradykinin or direct effect through the activation of prostaglandin synthesis.