In this study, 74 cows and 114 buffaloes were followed up during pregnancy and peripartum period at the Animal Farm, Faculty of Veterinary Medicine, Suez Canal University, Ismailia, EGYPT. Stillbirth rate was higher in cattle (10.81%) than that of buffaloes (4.38%). Late abortion accounted for 2.63% in buffaloes. An association between calving performance, anomalus fetus, weight of the placenta and stillbirth was found. Similarly, in both cattle and buffaloes, anemia was reported among the dams that showed abortion or stillbirth. In the mean time, meconium staining of the placenta was noticed in some stillbirths in buffaloes. Histopathologically, the placentae of the aborted animals revealed focal to diffuse necrosis in the epithelial covering along with degenerative change, circulatory disturbances and inflammatory reaction in the subepithelial tissue. The placental picture in stillbirth cases revealed vacuolar degeneration and/or necrosis of most trophoblasts with mononuclear leukocytic infiltration and blood vessels involvement. Chronic proliferative form of placentitis was not observed.