In this investigation, the BCG and Ultra-corn were evaluated for their effect on cellular and humeral immune responses in Rahmani lambs. The results obtained revealed that the BCG vaccinated lambs have an efficiently stimulated cell mediated or delayed hypersensitivity (DTH) than those
vaccinated with Ultra-corn. These lambs showed also a sharp increase in the lymphocyte and monocyte count at 7, 14, 21 and 28 days post-vaccination. On the other hand, both vaccines stimulated moderate increase of total immunoglobulins (Igs) and immunoglobulin-G (IgG) and consequently gamma-globulin, 14, 21 and 28 days post-vaccination.