A total of ninety samples (50 of minced beef and 40 of liver) were collected from randomly selected supermarkets and restaurant at Assiut city and examined for the presence of Listeria spp. Listeria spp. was of both minced beef and liver respectively. L. detected in 40% and 4% monocytogenes was recovered from 80% and 100% of the all positive samples of both minced beef and liver. The average number of colony   forming unit/gram (CFU/g) of L.monocytogenes were 5.2X10* and 1.6 X10% in both minced beef and liver respectively. Two methods of the enrichment for the isolation of Listeria spp. were performed. Pathogenicity of L. monocytogenes to mice was studied. The public health importance as well as recommended sanitary measures were discussed.