120, day old commercial broiler chicks were obtained and divided into two equal groups i.e. control (A) and treatment (B). Each chick of both groups was weighed and then dosed with one ml of either tryptose phosphate broth (A) or prepared inocula (B) at the same day. Chicks of both groups were housed separately under similar standard and managemental conditions. In the subsequent period of the experiment, it was observed that these severely effected birds had few ruffled, short broken shaft, mature wing feathers and in the later stages of experiment, these birds had pale combs, wattles and shanks. During 28 days experiment, 20% of the inoculated birds died while none of the bird died amongst control group. To determine the “Feed Conversion Ratio" FCR sufficient amount of feed was provided to each group and the remaining feed in feeding troughs was calculated at the same weekly intervals. It was statistically concluded that Feed Conversion Ratio was severely impaired in birds of group B which remained significantly lighter in the weight at all the stages of the experiment. Hence we can estimate a successful induction of the syndrome by a crude intestinal homogenate prepared of the affected birds under local conditions.