Trials for production of hyperimmune sera against Rift Valley Fever (RVF) virus in balady rabbits were done by using different types of adjuvants (saponin, IMS 3013, IMS 1113 and Freund's adjuvants). The concentration of saponin was 0.5% added to the vaccine while the other adjuvants were added in equal amounts to the vaccine. Each group of rabbits received four injections subcutaneously with one week interval, the first 3 injections were the mixture of inactivated virus and adjuvant but the last one was the virulent virus only. The level of antibody of the prepared hyperimmune sera was evaluated and determined by 3 different serological tests (serum neutralization test "SNT", ELISA and agar gel precipitation test). They revealed that the best of choice adjuvant was IMS3013 which gave high antibody titre at the 10^th-15^th day post last injection and persist till the 21^st day, the other types of adjuvants gave high level of antibody at 10^th day post injection but less in titre than that obtained by using IMS3013