An experiment was carried out to study the effect of Lasalocid on neonatal & milk production in Shami goats. Thirty pregnant female goats were divided into 3 groups each of 10 goats. First group was given 20 mg Lasalocid per head per day. Second group was given 40 mg Lasalocid per head per day. Third group was a control group. The effect on milk production was studied after one month of parturition. Another thirty goats were also divided into 3 groups each of 10 goats. Group one and two received 20 & 40 mg Lasalocid respectively and group one was used as a control. The results demonstrated that the addition of Lasalocid in the goats ration improved the live body weight (L.B.W.) of the neonatals at 21 & 42 days. The increase in L.B.W. was 176.7 & 246.6 g for group 1 & 2 respectively. At 21 days of age the increase in L.B.W was 516 & 748 g for the animals of group 1 & 2 respectively. At 42 days of age the improvement reached 1416.5 & 1395.8 g for group 1 & 2 respectively compared to control animals. Daily milk production was also increased when Lasalocid was given to milk goats for 220 & 200 for the group 1 & 2 after one week of parturition and it was 230 & 220 g for groups 1 & 2 after 2 wks. It was concluded that Lasalocid could be used in a small doses to improve not only the L.B.W of the neonatals goats but milk production as well.