The goal of the present study was to investigate the relation between the extent of liver and kidney damage in pregnancy toxemic does and the responsiveness of these does to therapeutic treatment. A total of 35 late pregnant does were included in this study from which, ten does were proved healthy and used as a control group. Blood samples were collected for separation of serum from all animals before and after therapeutic treatment. The following serum biochemical parameters were determined in the collected samples; enzyme activities of aspartate amino tansferase (AST), alanine amino tansferase (ALT), alkaline phosphatase (ALP). Blood urea nitrogen, creatinine, glucose, total lipid, triglycerides and total cholesterol levels were also measured. The results of the study have showed a direct relation between the extent of liver and kidney affection and the response of the pregnancy toxemic does to conventional therapeutic treatment.