Gross, light & scanning electron microscopic and immunohistochemical morphology of the non-ampullated part of the ductus deferens of sexually mature dromedary camels were studied with special reference to the changes and modifications occurring throughout its entire length. This part was subdivided into three anatomical regional segments; proximal tortuous (scrotal), middle less tortuous (inguinal) and distal straight (abdominal) segments. It characterized by simple and low folded mucosa. It lined by pseudostratified ciliated columnar epithelium with a thin lamina propria-submusosa. By scanning electron microscope, stereocilia of epithelial cells were tall and branched in the proximal segment tall, non-branched stereocilia in the middle segment and thick short microvilli in the distal segment. The muscular coat arranged in two layers; the inner layer was circular, while the outer layer was longitudinal. The intramural nerve fibers of the ductus deferens form plexuses in subepithelial tissue and in the muscular coat in addition larger nerve bundles in the serosa. Immunohistochemical reaction to protein gene product-9.5 (PGP-9.5) was used to demonstrate the general innervation pattern. The adrenergic and the cholinergic innervation were demonstrated using by immunohistochemical reactions to DPH and CHAT. These structural variations along the length of the vas deferens suggest that it performs functions other than just as a passageway for spermatozoa.