The aim of the present study was to determine the level of serum liver enzymes, triglyceride and some metabolites in cows with or without difficulties during parturition. The second goal was to compare between the possible effects of caesarian section and fetotomy on these parameters. A total number of 24 native breed cows at full term were included in this study. Out of these, 8 gave normal parturition, 16 cows were admitted for dystocia. The group of dystocia was subdivided into two groups: Fetotomy (n = 8) and caesarian (n = 8) group. In the caesarian group, 4 cows were with uterine torsion. Five blood samples were collected from each cow: directly prepartum, just after delivery and at, 24, 48 and 72 hrs postpartum. Serum samples were used for determination of aspartate amino transferase (AST, U/1), glutamate dehydrogenase (GLDH, U/1), gamma glutamyl transferase (y GT, U/l), creatine phosphokinase (CK, U/), glucose (mmol/l), total bilirubin (mmol/l), cholesterol (mmol/l) and triglyceride (mmol/l). The results showed that caesarian group revealed significant increase in serum activities of AST, GLDH and CK (p < 0.001) and y GT (p < 0.01) in prepartum period than the other groups. There were significant differences between group with normal parturition and the other groups with regard to activities of AST and GLDH, (p < 0.001), y GT and CK (p < 0.05) and glucose level (p < 0.05) post partum. There were no significant differences in the bilirubin, cholesterol and triglyceride levels in all tested groups at all times of sampling. Analysis of samples from fetotomy group revealed no significant increases in serum activities of all tested liver enzymes except the significant increase in glucose level (p < 0.01). In conclusion, cattle subjected to caesarian section and especially those with uterine torsion are suffer from hepatic dysfunction. On the other hand, fetotomy has no effect on hepatocelluar damage. The type of parturition has no effect on the bilirubin, cholesterol and triglyceride concentration just before parturition to the 3rd day post partum.