Monitoring levels of mineral concentrations in animal tissues is important for assessing the effect of contamination on animal health and safety of animal origin products in human nutrition. This study evaluated the levels of copper in cattle, buffaloes, camels, sheep and goats reared in Ismailia Governorate, Egypt. Samples of 303 animals aged 6-36 months were collected from the Governorate slaughterhouse at slaughtering and analyzed after acid digestion using atomic absorption spectrophotometer (AAS). The mean concentrations obtained per wet weight (ppm) for liver, kidney, muscle, hair, serum were 31.33, 10.87, 5.55, 7.44 and 0.90in camels; 27.61, 6.01, 4.10, 7.84, and 0.79 in buffaloes ; 25.10, 5.61, 4.52, 6.92 and 0.78 in cows; 37.44, 8.08, 7.235, 10.03 and 0.75insheep and 25.23, 3.62, 4.75, 6.33 and 0.64 in goats. The highest concentration of copper was in liver while the lowest was in hair for all animals. The results indicated that sheep had the higher liver copper concentrations, followed by camels, buffaloes, goats and then cows.